Demi Moore gave a moving speech as she accepted her first Golden Globe win for her critically-acclaimed performance in the body horror film, The Substance.
The actress, 62 - who looked ageless as she walked the glamorous red carpet ahead of the main ceremony - became emotional as she clutched the statue in her hand after winning Best Actress in a Motion Picture - Musical or Comedy.
Her daughters Rumer, 36, Scout, 33, and Tallulah, 30, were also filmed reacting to their mother garnering her first major acting award since starting her career in the 1980s.
After stepping onto the stage, Moore was greeted by applause from the celebrity guests and admitted, 'Wow, I really wasn't expecting that.'
'I'm just in shock right now. I've been doing this a long time, like over 45 years and this is the first time I've ever won anything as an actor.'
'I'm just so humbled and so grateful,' she added before recalling how a producer had once called her a 'popcorn actress' in the past.
Demi Moore, 62, gave a moving speech as she accepted her first Golden Globe win for her critically-acclaimed performance in the body horror film, The Substance
Her daughters Rumer, 36, Scout, 33, and Tallulah, 30, were also filmed reacting to their mother garnering her first major acting award since starting her career in the 1980s
Moore said that at the time, she felt 'this wasn't something that I was allowed to have, that I could do movies that were successful, that made a lot of money, but that I couldn't be acknowledged.'
'And I bought in, and I believed that, and that corroded me over time, to the point where I thought a few years ago that maybe this was it, maybe I was complete, maybe I've done what I was supposed to do.'
She recalled, 'And as I was at kind of a low point, I had this magical, bold, courageous, out of the box, absolutely bonkers script come across my desk called The Substance, and the universe told me that you're not done.'
Demi then gave a special shout out to the director, Coralie Fargeat, 'for trusting me, to step in and play this woman.'
She also thanked her co-star, Margaret Qualley, for 'looking out for me' as well as 'all the people who stood by me, especially the people who believed in me when I haven't believed in myself.'
Towards the end of her touching speech, the Ghost actress added, 'I'll just leave you with one thing.'
'That I think this movie is imparting is in those moments when we don't think we're smart enough or pretty enough or skinny enough or successful enough, or basically just not enough.'
'I had a woman say to me, "Just know you will never be enough, but you can know the value of your worth if you just put down the measuring stick."'
'I'm just in shock right now. I've been doing this a long time, like over 45 years and this is the first time I've ever won anything as an actor,' she stated
She also thanked her co-star, Margaret Qualley, for 'looking out for me' as well as 'all the people who stood by me, especially the people who believed in me when I haven't believed in myself'
'I had a woman say to me, "Just know you will never be enough, but you can know the value of your worth if you just put down the measuring stick,"' Demi recalled
A joint post was soon uploaded to Instagram that captured the moment her daughters reacted to their mother's Golden Globe win
The second Demi's name was read, everyone threw their arms into the air and jumped to their feet. Loud cheers and screams echoed around the room during the exciting moment
GOLDEN GLOBES 2025 WINNERS: AT A GLANCE
FILM
Best Film - Drama: The Brutalist
Best Film - Musical or Comedy: Emilia Pérez
Best Non-English Language Film: Emilia Pérez
Best Actress - Musical or Comedy: Demi Moore, The Substance
Best Supporting Actress - Musical or Comedy: Zoe Saldaña, Emilia Pérez
Best Actor - Drama: Adrien Brody, The Brutalist
Best Actress - Drama: Fernanda Torres, I'm Still Here
Cinematic And Box Office Achievement: Wicked
Best Actor - Musical or Comedy: Sebastian Stan, A Different Man
Best supporting Actor - Musical or Comedy: Kieran Culkin, A Real Pain
Emilia Perez led the way on the film side with four awards including Best Film - Musical or Comedy
'And so today,' Moore continued, 'I celebrate this as a marker of my wholeness and of the love that is driving me and for the gift of doing something I love and being reminded that I do belong. Thank you so much.'
A joint post was soon uploaded to Instagram that captured the moment her daughters reacted to their mother's Golden Globe win.
The clip was shared by Moore's friends, Amanda De Cadenet and Eric Buterbaugh, as well as her three daughters - whom she shares with ex Bruce Willis.
Rumer, Scout and Tallulah could be seen sitting on the floor of a spacious living room along with other close family friends while looking at a TV.
The group remained quiet as they awaited for the presenters on stage to announce the winner of Best Actress in a Musical or Comedy.
The second Demi's name was read, everyone threw their arms into the air and jumped to their feet. Loud cheers and screams echoed around the room during the exciting moment.
Her daughters quickly sat back down on the floor to begin listening to Moore's acceptance speech.
In the comment section of the joint post, Scout penned, 'SHE DID IT,' followed by crying face emojis.
Scout also added, 'this is a huge win for EVERYONE,' while Tallulah shared, 'I love her so f***ing much, I have no words'
Demi has been nominated for a total of four Golden Globes throughout her career thus far, winning her first on Sunday. She has also garnered Emmy and SAG Award nods over the years
The movie was nominated for an additional four Golden Globes, such as Best Supporting Actress for Qualley
Rumer wrote, 'GO MAMA GO. So so proud of you. Omg I love you so much. So well deserved.'
Scout also added, 'this is a huge win for EVERYONE,' while Tallulah shared, 'I love her so f***ing much, I have no words.'
Demi has been nominated for a total of four Golden Globes throughout her career thus far, winning her first on Sunday. She has also garnered Emmy and SAG Award nods over the years.
The Substance was released in theaters last year in September 2024, and the cast also included Margaret Qualley, Dennis Quaid, Hugo Diego Garcia and Oscar Lesage.
The premise of the movie is: 'A fading celebrity takes a black-market drug: a cell-replicating substance that temporarily creates a younger, better version of herself,' per IMDB.
The movie was nominated for an additional four Golden Globes, such as Best Supporting Actress for Qualley.
Before taking on her role in The Substance, Demi had thought her Hollywood career was 'complete'
She added, 'And I thought, "You know what? Maybe my time doing this is complete. Maybe I've done everything I was supposed to do." … Two weeks later, the script for The Substance came across my desk'
Before taking on her role in The Substance, Demi had thought her Hollywood career was 'complete.'
She touched on the topic while accepting the Maria Manetti Shrem Award for Acting during the SFFILM Awards in San Francisco in December.
The star expressed, 'I've had a very long career, but I haven't really ever been part of the conversations that allowed me to be part of [awards shows] and to really receive the love and celebration of my work. I'm really just so humbled.'
'At the beginning of 2022, I had a moment where I was at an event and I felt I didn't belong. I didn't know why I was there. I wanted to be invisible and I couldn't figure out how to get out.'
Moore took to the stage once again during the special night alongside Qualley as they presented the award for Best Actor in a Television Series - Drama, which went to Hiroyuki Sanada
She added, 'And I thought, "You know what? Maybe my time doing this is complete. Maybe I've done everything I was supposed to do." … Two weeks later, the script for The Substance came across my desk.'
Demi admitted she had been 'almost ready to step away' but told the crowd that she was grateful she chose not to.
Moore took to the stage once again during the special night on Sunday alongside Qualley as they presented the award for Best Actor in a Television Series - Drama, which went to Hiroyuki Sanada.
And inside one of the ballrooms inside the iconic Beverly Hilton Hotel, Margaret and Demi held big smiles on their faces for a memorable snap together.
GOLDEN GLOBES 2025 WINNERS
FILM
Best Film - Drama
The Brutalist - WINNER
A Complete Unknown
Conclave
Dune: Part Two
Nickel Boys
September 5
Best Film - Musical or Comedy
Anora
Challengers
Emilia Pérez - WINNER
A Real Pain
The Substance
Wicked
Emilia Perez earned top honor Best Film - Musical or Comedy
Best Non-English Language Film
All We Imagine as Light
Emilia Pérez - WINNER
The Girl with the Needle
I'm Still Here
The Seed of the Sacred Fig
Vermiglio
Best Animated Film
Flow - WINNER
Inside Out 2
Memoir of a Snail
Moana 2
Wallace & Gromit: Vengeance Most Fowl
The Wild Robot
Cinematic And Box Office Achievement
Alien: Romulus
Beetlejuice Beetlejuice
Deadpool & Wolverine
Gladiator II
Inside Out 2
Twisters
Wicked - WINNER
The Wild Robot
Best Actress - Drama
Pamela Anderson, The Last Showgirl
Angelina Jolie, Maria
Nicole Kidman, Babygirl
Tilda Swinton, The Room Next Door
Fernanda Torres, I'm Still Here - WINNER
Kate Winslet, Lee
Best Actor - Drama
Adrien Brody, The Brutalist - WINNER
Timothée Chalamet, A Complete Unknown
Daniel Craig, Queer
Colman Domingo, Sing Sing
Ralph Fiennes, Conclave
Sebastian Stan, The Apprentice
Adrien Brody was recognized in the Best Actor - Drama category for The Brutalist
Best Actress - Musical or Comedy
Amy Adams, Nightbitch
Cynthia Erivo, Wicked
Karla Sofía Gascón, Emilia Pérez
Mikey Madison, Anora
Demi Moore, The Substance - WINNER
Zendaya, Challengers
Best Actor - Musical or Comedy
Jesse Eisenberg, A Real Pain
Hugh Grant, Heretic
Gabriel LaBelle, Saturday Night
Jesse Plemons, Kinds of Kindness
Glen Powell, Hit Man
Sebastian Stan, A Different Man - WINNER
Best Supporting Actress - Musical or Comedy
Ariana Grande, Wicked
Selena Gomez, Emilia Pérez
Felicity Jones, The Brutalist
Margaret Qualley, The Substance
Isabella Rossellini, Conclave
Zoe Saldaña, Emilia Pérez - WINNER
Zoe Saldana was crowned Best Supporting Actress - Musical or Comedy for Emilia Perez
Best supporting Actor - Musical or Comedy
Yura Borisov, Anora
Kieran Culkin, A Real Pain - WINNER
Edward Norton, A Complete Unknown
Guy Pearce, The Brutalist
Jeremy Strong, The Apprentice
Denzel Washington, Gladiator II
Best director
Jacques Audiard, Emilia Pérez
Sean Baker, Anora
Edward Berger, Conclave
Brady Corbet, The Brutalist - WINNER
Coralie Fargeat, The Substance
Payal Kapadia, All We Imagine as Light
Best screenplay
Jacques Audiard, Emilia Pérez
Sean Baker, Anora
Brady Corbet, Mona Fastvold, The Brutalist
Jesse Eisenberg, A Real Pain
Coralie Fargeat, The Substance
Peter Straughan, Conclave - WINNER
Best Original Song
Beautiful That Way, The Last Showgirl
Compress/Repress, Challengers
El Mal, Emilia Pérez - WINNER
Forbidden Road, Better Man
Kiss The Sky, The Wild Robot
Mi Camino, Emilia Pérez
Best Original Film Score
Conclave
The Brutalist
The Wild Robot
Emilia Pérez
Challengers - WINNER
Dune: Part Two
TV
Best TV Series - Drama
The Diplomat
Mr. and Mrs. Smith
Shōgun - WINNER
Squid Game
Slow Horses
The Day of the Jackal
Shōgun was the most honored television series with four including coveted Best TV Series - Drama
Best TV Series - Comedy or Musical
Abbott Elementary
The Bear
The Gentlemen
Hacks - WINNER
Nobody Wants This
Only Murders in the Building
Best Limited TV Series
Baby Reindeer - WINNER
Disclaimer
Monsters: The Lyle and Erik Menendez Story
The Penguin
Ripley
True Detective: Night Country
Best TV Actress - Drama
Kathy Bates, Matlock
Emma D'Arcy, House of the Dragon
Maya Erskine, Mr. and Mrs. Smith
Keira Knightley, Black Doves
Anna Sawai, Shōgun - WINNER
Keri Russell, The Diplomat
Best TV Actor – Drama
Donald Glover, Mr. and Mrs. Smith
Jake Gyllenhaal, Presumed Innocent
Gary Oldman, Slow Horses
Eddie Redmayne, The Day of the Jackal
Hiroyuki Sanada, Shōgun - WINNER
Billy Bob Thornton, Landman (Paramount+)
Best TV Actress - Comedy or Musical
Kristen Bell, Nobody Wants This
Quinta Brunson, Abbott Elementary
Ayo Edebiri, The Bear
Selena Gomez, Only Murders in the Building
Kathryn Hahn, Agatha All Along
Jean Smart, Hacks - WINNER
Jean Smart earned Best TV Actress - Comedy or Musical for Hacks
Best TV Actor - Comedy or Musical
Adam Brody, Nobody Wants This
Ted Danson, A Man on the Inside
Steve Martin, Only Murders in the Building
Jason Segel, Shrinking
Martin Short, Only Murders in the Building
Jeremy Allen White, The Bear - WINNER
Best TV Actress - Limited Series
Cate Blanchett, Disclaimer
Jodie Foster, True Detective: Night Country - WINNER
Cristin Milioti, The Penguin
Sofía Vergara, Griselda
Naomi Watts, Feud: Capote vs. The Swans
Kate Winslet, The Regime
Best TV Actor - Limited Series
Colin Farrell, The Penguin - WINNER
Richard Gadd, Baby Reindeer
Kevin Kline, Disclaimer
Cooper Koch, Monsters: The Lyle and Erik Menendez Story
Ewan McGregor, A Gentleman in Moscow
Andrew Scott, Ripley
Best Supporting Actress - TV
Liza Colón-Zayas, The Bear
Hannah Einbinder, Hacks
Dakota Fanning, Ripley
Jessica Gunning, Baby Reindeer - WINNER
Allison Janney, The Diplomat
Kali Reis, True Detective: Night Country
Jessica Gunning took home Best Supporting Actress - TV for her incredible work on Baby Reindeer
Best Supporting Actor - TV
Tadanobu Asano, Shōgun - WINNER
Javier Bardem, Monsters: The Lyle and Erik Menendez Story
Harrison Ford, Shrinking
Jack Lowden, Slow Horses
Diego Luna, La Maquina
Ebon Moss-Bachrach, The Bear
Best TV Stand-Up Comedy Performance
Jamie Foxx, What Had Happened Was
Nikki Glaser, Someday You'll Die
Seth Meyers, Dad Man Walking
Adam Sandler, Love You
Ali Wong, Single Lady - WINNER
Ramy Youssef, More Feelings
Ali Wong beat out Nikki Glaser for Best TV Stand-Up Comedy Performance