The Sisterhood faces a powerful foe in Dune: Prophecy trailer

New York Comic-Con kicked off today and among the highlights was an HBO panel devoted to the platform's forthcoming new series, Dune: Prophecy—including the release of a two-and-a-half-minute trailer.

As previously reported, the series was announced in 2019, with director Denis Villeneuve serving as an executive producer and Alison Schapker (Alias, Fringe, Altered Carbon) serving as showrunner. It's a prequel series inspired by the novel Sisterhood of Dune, written by Brian Herbert and Kevin J. Anderson, exploring the origins of the Bene Gesserit.  The first season will have six episodes, and it's unclear how closely the series will adhere to the source material. Per the official premise:

Set 10,000 years before the ascension of Paul Atreides, Dune: Prophecy follows two Harkonnen sisters as they combat forces that threaten the future of humankind, and establish the fabled sect that will become known as the Bene Gesserit.

Emily Watson co-stars as Valya Harkonnen, leader of the Sisterhood, with Olivia Williams playing her sister, Tula Harkonnen. Mark Strong plays Emperor Javicco Corrino, while Jodhi May plays Empress Natalya, and Sarah-Sofie Boussnina plays Princess Ynez.

The cast also includes Shalom Brune-Franklin as Mikaela, a Fremen woman who serves the royal family; Travis Fimmel as Desmond Hart, "a charismatic soldier with an enigmatic past"; Chris Mason as swordsman Keiran Atreides; Josh Heuston as Constantine Corrino, the illegitimate son of Javicco; Edward Davis as rising politician Harrow Harkonnen; Tabu as Sister Francesca, the Emperor's former lover; Jihae as Reverend Mother Kasha, the Emperor's Truthsayer; Faoileann Cunningham as Sister Jen; Chloe Lea as Lila; Jade Anouka as Sister Theodosia; and Aoife Hinds as Sister Emeline.