Salma Hayek was a dazzling bombshell alongside glamorous Gigi Hadid and Anne Hathaway as they led stars at the 12th Annual Breakthrough Prize Ceremony in Santa Monica on Saturday.
The 59-year-old actress posed up a storm with the model, 30, and Oscar winner, 43 - who is preparing for the release of the anticipated sequel The Devil Wears Prada 2.
The event - which is also known as the 'Oscars of Science' - helps 'honor scientists whose discoveries are significantly driving growth of human knowledge,' per the official website.
Hayek turned heads wearing a figure-hugging, black lace gown that clung to her figure and contained sequin details on the material.
Velvet-layered embellishments were added around the neckline and her dark locks were swept up into a chic updo.
The Frida actress accessorized the look with a pair of dangly silver earrings as well as a matching bracelet and a few chunky rings on each of her hands.
Salma Hayek, 59, was a dazzling bombshell alongside glamorous Gigi Hadid, 30, and Anne Hathaway, 43, as they led stars at the 12th Annual Breakthrough Prize Ceremony in Santa Monica on Saturday
Her makeup was glammed up for the special evening and comprised of a layer of mascara to her lashes as well as a smoky shadow around her eyes.
A warm blush was added to better accentuate her cheekbones while a nude-colored, matte tint was worn on her lips for a finishing touch.
Hayek flashed a cheerful smile as she showed off her ensemble upon arriving to the festivities.
The star was accompanied by her husband Francois-Henri Pinault who was dressed for the occasion in a classic black suit as well as a white shirt and black bowtie.
Hadid was radiant as she stepped onto the red carpet in a halter-styled white gown and slipped into a pair of open-toed, white pumps.
A sparkling embellishment was added towards the top of the dress and her blonde locks were partially pulled back away from her face into a half updo.
The supermodel opted for a pair of small, silver earrings as well as a dainty bracelet on her left wrist.
A layer of mascara was added to her lashes while a darker nude-colored tint was worn on her lips.
Hayek turned heads wearing a figure-hugging, black lace gown that clung to her figure and contained sequin details on the material
Velvet-layered embellishments were added around the neckline and her dark locks were swept up into a chic updo
Her makeup was glammed up for the special evening and comprised of a layer of mascara to her lashes as well as a smoky shadow around her eyes
The star was accompanied by her husband Francois-Henri Pinault who was dressed for the occasion in a classic black suit as well as a white shirt and black bowtie
Hayek flashed a cheerful smile as she showed off her ensemble upon arriving to the festivities
Hadid was radiant as she stepped onto the red carpet in a halter-styled white gown and slipped into a pair of open-toed, white pumps
The supermodel opted for a pair of small, silver earrings as well as a dainty bracelet on her left wrist
A layer of mascara was added to her lashes while a darker nude-colored tint was worn on her lips
Hathaway was elegant in a one-shoulder, black dress as well as a pair of open-toed, black heels
Hathaway was elegant in a one-shoulder, black dress as well as a pair of open-toed, black heels.
Her dark locks were parted to the side and effortlessly cascaded down past her shoulders in light waves.
The Princess Diaries actress carried a black clutch in her hand and added mini sparkling earrings to the outfit.
Silver and gold bracelets were added to her left wrist for a final touch as she posed for a brief photo session at the gala.
A light pink blush was added to her cheekbones for a radiant glow while a rosy pink tint was worn on her lips.
Christina Aguilera made a statement in a dress that comprised of a black leather, corset bodice and sheer skirt which flowed down into a train behind her.
Her short blonde hair curled into elegant waves while her bangs fell down straight onto her forehead.
The Genie In A Bottle hitmaker opted for a dazzling necklace with a black pendant as well as a small silver bracelet on her left wrist.
Aguilera was joined by partner Matthew Rutler on the red carpet as the couple stopped for a few snaps together.
Her dark locks were parted to the side and effortlessly cascaded down past her shoulders in light waves
Christina Aguilera made a statement in a dress that comprised of a black leather, corset bodice and sheer skirt which flowed down into a train behind her
The Genie In A Bottle hitmaker opted for a dazzling necklace with a black pendant as well as a small silver bracelet on her left wrist
Aguilera was joined by partner Matthew Rutler on the red carpet as the couple stopped for a few snaps together.
Rutler donned a classic black suit and was later seen laying a gentle kiss on the singer's cheek in a sweet moment
Rutler donned a classic black suit which was paired with a white dress shirt as well as black boots.
Paris Hilton also stopped by the festivities wearing a shimmering black corset as well as a matching skirt that pooled around her.
Her blonde locks flowed past her shoulders in light curls and she also opted for black, elbow-length velvet gloves.
The Simple Life alum accessorized the outfit with a sparkling necklace as well as matching earrings.
Lily Collins was elegant in a greenish strapless dress and also donned a pair of open-toed, black pumps.
She further glammed up the ensemble by adding chunky gold and silver earrings as well as a matching ring on her right hand.
The Emily In Paris actress was accompanied by husband Charlie McDowell who donned a double-breasted black suit and black ribbon tie.
Gal Gadot was in attendance in a cropped black blazer as well as a flowy black skirt that fell down to brush the ground.
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Paris Hilton also stopped by the festivities wearing a shimmering black corset as well as a matching skirt that pooled around her
Hilton further flaunted her look for the night as she was joined by husband Carter Reum
Lily Collins was elegant in a greenish strapless dress and also donned a pair of open-toed, black pumps
Gal Gadot was in attendance in a cropped black blazer as well as a flowy black skirt that fell down to brush the ground
Jessica Chastain was stylish in a strapless tan dress with a fringed hem and gold embroidery on the thick material
Jessica Chastain was stylish in a strapless tan dress with a fringed hem and gold embroidery on the thick material.
Her reddish locks were parted to the side and the actress also added a dainty silver necklace.
Chrissy Teigen flashed a big smile wearing a strapless nude-colored dress with a thigh-high slit on the right side.
Her brunette hair was parted in the middle and styled into a chic updo, allowing wavy strands to border the sides of her face.
She was seen with husband John Legend who was dapper in a black suit as well as a white dress shirt and black bowtie.
Michelle Yeoh was spotted waring a pair of black satin trousers as well as a black blazer.
The Wicked actress added a lace top underneath and slipped into a pair of closed-toed, black pumps while a chunky gold necklace added a fashionable flare.
Olivia Wilde donned a strapless dress with a corset bodice that had sparkling details and a flowy patterned skirt.
Chrissy Teigen flashed a big smile wearing a strapless nude-colored dress with a thigh-high slit on the right side
Michelle Yeoh was spotted waring a pair of black satin trousers as well as a black blazer and lace top underneath
Olivia Wilde donned a strapless dress with a corset bodice that had sparkling details and a flowy patterned skirt
The actress added a dainty necklace to the look and slipped into a pair of closed-toed, black heels.
Octavia Spencer donned a pair of black trousers as well as a black top and shimmering black blazer.
The star also wore a pair of open-toed, black pumps and allowed her locks to flow down past her shoulders in elegant curls.
Behati Prinsloo wowed in a dark tan, satin gown that clung to her figure and her blonde locks cascaded down in light waves.
The model flashed a big grin as husband Adam Levine accompanied her on the red carpet and planted a loving kiss on her cheek.
Miranda Kerr exuded old Hollywood glam in a strapless blue dress that had fabric that flowed down behind her into a train.
The star opted for black heels and allowed her long locks to cascade past her shoulders in natural waves.
Kerr was seen posing with husband Evan Spiegel - whom she tied the knot with back in 2017.
The actress added a dainty necklace to the look and slipped into a pair of closed-toed, black heels
Octavia Spencer donned a pair of black trousers as well as a black top and shimmering black blazer
Behati Prinsloo wowed in a dark tan, satin gown that clung to her figure and her blonde locks cascaded down in light waves
The model flashed a big grin as husband Adam Levine accompanied her on the red carpet and planted a loving kiss on her cheek
The Maroon 5 singer was dressed in a classic black suit as well as a light blue shirt and sleek loafers
Miranda Kerr exuded old Hollywood glam in a strapless blue dress that had fabric that flowed down behind her into a train
Kerr was seen posing with husband Evan Spiegel - whom she tied the knot with back in 2017
Elsa Collins turned heads wearing a sleeveless black gown with a deep plunging neckline on the front.
She opted for black heels and allowed her dark locks to flow down behind her in light waves.
Singer Jewel was radiant wearing a vibrant yellow dress that contained a daring cutout on the right side for a sultry flare.
She slipped into open-toed, gold pumps and easily carried a shimmering gold clutch in her hand.
At one point, the songstress was seen crossing paths with Nvidia CEO Jensen Huang on the red carpet.
Susan Downey struck a pose donning a black dress that was held up with thin straps that wrapped around her shoulders.
She also sweetly held hands with husband Robert Downey Kr. who wore a black suit with a dark gold saint shirt and black tie.
Katharine McPhee was stylish in a white floral dress that contained a sparkling silver trim around the neckline.
She was joined by husband David Foster who sported a classic black suit as well as a white shirt and black dress shoes.
Elsa Collins turned heads wearing a sleeveless black gown with a deep plunging neckline on the front
Singer Jewel was radiant wearing a vibrant yellow dress that contained a daring cutout on the right side for a sultry flare
At one point, the songstress was seen crossing paths with Nvidia CEO Jensen Huang on the red carpet
Susan Downey struck a pose donning a black dress that was held up with thin straps that wrapped around her shoulders
Katharine McPhee was stylish in a white floral dress that contained a sparkling silver trim around the neckline
She was joined by husband David Foster who sported a classic black suit as well as a white shirt and black dress shoes
Gayle King donned a purple-patterned, strapless dress and carried a black clutch in her hand for the event on Saturday.
Wendi Deng Murdoch wore a nude-colored dress that contained silver embellishments on the material.
A slit on the left side offered a glimpse at silver pumps and she accessorized the look with chunky earrings and a silver necklace.
Naomi Watts a sleeveless dark gray dress with a bedazzled collar and as she turned away from the camera, she gave a glimpse at the semi backless portion of the outfit.
The King Kong actress carried a mini purse in her hand and was joined by husband Billy Crudup.
Julie Kim wore a black halter-styled dress made of satin material and styled her dark locks into a chic updo.
Emma Walmsley was fashionable in a dark red sequin ensemble and opted for nude-colored heels.
Zoe Saldana turned heads in a strapless yellow dress with husband Marco Perego-Saldana who opted for a black tuxedo and loosened black shirt.
Gayle King donned a purple-patterned, strapless dress and carried a black clutch in her hand for the event on Saturday
Wendi Deng Murdoch wore a nude-colored dress that contained silver embellishments on the material
Naomi Watts a sleeveless dark gray dress with a bedazzled collar and as she turned away from the camera, she gave a glimpse at the semi backless portion of the outfit
The King Kong actress carried a mini purse in her hand and was joined by husband Billy Crudup
Julie Kim wore a black halter-styled dress made of satin material and styled her dark locks into a chic updo
Zoe Saldana turned heads in a strapless yellow dress with husband Marco Perego-Saldana who opted for a black tuxedo and loosened black shirt
Sheryl Berkoff dressed for the occasion wearing a shimmering black gown while Rob Lowe sported a black suit as well as a white shirt and black tie.
Lisa Parigi was elegant in a cream-colored ensemble that contained caped details alongside Lionel Richie.
The All Night Long singer donned a double-breasted black suit as well as a white shirt underneath.
Bill Gates wore a black suit and black shirt while Paula Hurd color-coordinated in a black dress.
Shawn Levy was dapper in a classic black suit while Serena Levy donned a strapless ruched dress with red floral details.
Oscar Isaac made a statement in a sleek double-breasted tuxedo alongside stylish Elvia Lind at the event.
Sam Sheridan wore a black suit while Patty Jenkins donned a silver gown with caped fabric around her shoulders.
Edward Norton also opted for a classic black suit for the ceremony while his wife Shauna Robertson was chic in a shimmering, dark green gown.
Sheryl Berkoff dressed for the occasion wearing a shimmering black gown while Rob Lowe sported a black suit as well as a white shirt and black tie
Lisa Parigi was elegant in a cream-colored ensemble that contained caped details alongside Lionel Richie
Bill Gates wore a black suit and black shirt while Paula Hurd color-coordinated in a black dress
Shawn Levy was dapper in a classic black suit while Serena Levy donned a strapless ruched dress with red floral details
Oscar Isaac made a statement in a sleek double-breasted tuxedo alongside stylish Elvia Lind at the event
Edward Norton also opted for a classic black suit for the ceremony while his wife Shauna Robertson was chic in a shimmering, dark green gown
Barbara Muschietti wowed in a shimmering gold dress with Arthur Phillips on the red carpet.
Alexa Dell opted for a flowy gray dress while Fred Choquette donned a classic black suit and bowtie.
Iris Knobloch wore a pastel pink dress with colorful floral details with Francois Breavoine at the event.
Alexis Traina slipped into a one-shoulder black dress while Trevor Traina was also dapper in a black suit for the evening.
Anna Brockman posed on the red carpet in a gold dress held up with thin straps with Greg Brockman who sported a black suit.
Glara Ahn wore a cheetah-print dress with bow pieces on her shoulders alongside Matt Huang.
Zanny Minton was spotted in a shimmering silver dress and silver heels with Sebastian Mallaby.
Brian Grazer flashed a peace sign in a dark navy suit with Veronica Smiley Grazer who donned a fitted black dress.
Barbara Muschietti wowed in a shimmering gold dress with Arthur Phillips on the red carpet
Alexa Dell opted for a flowy gray dress while Fred Choquette donned a classic black suit and bowtie
Iris Knobloch wore a pastel pink dress with colorful floral details with Francois Breavoine at the event
Anna Brockman posed on the red carpet in a gold dress held up with thin straps with Greg Brockman who sported a black suit
Glara Ahn wore a cheetah-print dress with bow pieces on her shoulders alongside Matt Huang
Zanny Minton was spotted in a shimmering silver dress and silver heels with Sebastian Mallaby
Brian Grazer flashed a peace sign in a dark navy suit with Veronica Smiley Grazer who donned a fitted black dress
Ben Affleck was spotted posing solo on the red carpet in a classic black suit as well as a white dress shirt and small black bowtie
Orlando Bloom additionally wore a black suit at the event as well as a black tie and sleek dress shoes
Grazer also flashed a big smile as he paused for a lighthearted photo with filmmaker Ron Howard.
Ben Affleck was spotted posing solo on the red carpet in a classic black suit as well as a white dress shirt and small black bowtie.
Orlando Bloom additionally wore a black suit at the event as well as a black tie and sleek dress shoes.
Andrew Taggart was dapper in a suit which he paired with a white shirt and black bowtie for the special evening.

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