Big Bang Theory vet Kaley Cuoco talks lowest point in her life that left her 'sobbing on the floor'

Kaley Cuoco just revealed the lowest point in her life was in April 2022 - two months before she finalized her divorce from second ex-husband Karl Cook after three years of marriage.

At the time, the 40-year-old Big Bang Theory alum was still living in their marital home, and she was lying on the floor despondent.

'I was on the floor sobbing, thinking I ruined my whole life,' Cuoco confessed on the Armchair Expert podcast Monday.

'That is the lowest point of my life I ever had. I couldn't get up. I was so depressed.'

The three-time Emmy nominee had to get it together so she could glam up for the second season premiere of her HBO Max show The Flight Attendant in West Hollywood.

'My hair and makeup girls came over. They were literally doing my hair makeup on the floor,' Cuoco recalled.

'I said, "I can't go." I was so sad. The path for me was so complicated. And I just thought, "Oh, man, this might've been it for me."'

However, the Harley Quinn producer-star has 'not a single bad thing to say about' the 35-year-old equestrian, clarifying: 'He's amazing.'

By September 2022, Cook had moved on with MiResource founder Mackenzie Drazan, whom he wed in April 2024.

And it only took Cuoco two weeks to meet her fiancé Tom Pelphrey while attending the fourth season premiere of his Netflix show Ozark in Manhattan on the encouragement of her manager.

'I get this feeling that I'm gonna spend my life with him,' the Cali native said scanning his Instagram account.

'And I texted my best friend, Sasha, in that moment. She still has it, and I said, "This is crazy, but I have to put it in writing. I think I'm gonna meet the man I'm gonna spend my life with." She goes, "What do mean?" I'm like, "Just keep this text." And it was Tom. And I met him two weeks later.'

On March 30, Cuoco and the 43-year-old Emmy nominee will celebrate the third birthday of their daughter Matilda Carmine Richie Pelphrey, whom they got pregnant with 'an hour later.'

'I never thought I would have kids. I always loved them, but I felt like I missed the mark,' The Yes Norman Productions founder noted.

'But I met Tom. We both wanted it so bad. And then we got pregnant easily, and we're so excited.'

Cuoco previously dated her BBT castmate Johnny Galecki, addiction specialist Josh Resnik, Superman alum Henry Cavill and she was married tennis pro Ryan Sweeting.

The eight-time Actor Award nominee executive produces and stars as American in Paris Alice Monroe in David Hilton and Preston Thompson's mystery drama Vanished, which airs Sundays on MGM+.

The conspiracy miniseries currently has a dismal 42 percent critic approval rating (out of 12 reviews) on Rotten Tomatoes.

HBO Max has yet to renew Paul Dini and Bruce Timm's adult animated series Harley Quinn for a sixth season, so it's unclear if Cuoco will be back as the titular bisexual DC Comics character.